I have everything maxed out. Antialising is on x8 which is all the way, and anstrinopic or however you spell it filtering is on x8 but it can go up to x18.
I have shadows on medium though. Turning them down one notch from High was like 10 - 20 fps boost and still looks alright.
If anyone wants to upgrade their graphics cards so they can play the game on higher settings at least get a GTX 460 or a Radeon 6850
Also, I saw some orange reddish ones near some town (I forgot the name at the moment, but you go there to start the dark brotherhood quest, that kid whos rececting the chants)
I wouldn't say that
6950 at minimum
my card(MSI Cyclone 6850) struggles like fuck at full max without AA
8FPS @ 1080p
however, lowering shadows to high and disabling the HBAO shiz fixed it back up to 60 average with textures etc still on ultra